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PDF] EVIDENCE FOR THE BIOACTIVATION OF ZOMEPIRAC AND TOLMETIN BY AN OXIDATIVE PATHWAY: IDENTIFICATION OF GLUTATHIONE ADDUCTS IN VITRO IN HUMAN LIVER MICROSOMES AND IN VIVO IN RATS | Semantic Scholar

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Clinical findings or diagnostic testing abnormalities consistent with a documented route of exposure should support a diagnosis of cobalt toxicity, although these may be nonspecific (e.g., cardiomyopathy, pulmonary function abnormalities in cobalt lung disease, thyroid dysfunction, patch testing for sensitization, etc.)