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Glycine helps support methionine clearance in the body through the enzyme glycine N-methyltransferase (Gnmt)
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For instance, combining myo-inositol with folic acid in PCOS patients modulates extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation, reducing phosphorylated AKT levels and improving insulin sensitivity, a key factor in PCOS-associated infertility (Unfer et al., 2017)
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