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Mitochondrial activity and glycolytic parameters were measured by the oxygen consumption rate (OCR) (pmol/min) and extracellular acidification rate (ECAR) (mpH/min), respectively, with use of real-time injections of oligomycin (1.5 mM), carbonyl cyanide ptrifluoromethoxyphenylhydrazone (FCCP
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Tamoxifen is the prototypical SERM that has both agonistic and antagonistic effects depending on the tissue, for example in breast tissue, tamoxifen exhibits an antagonistic effect [7]
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