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To date, there is little known about the exact mechanisms underlying PD and the associated fibrotic conditions
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Moreover, ageing tended to amplify the depletion of blood GSH and modified the pattern of urinary APAP conjugates in favour of an increased loss of Cys in postoperative patients under intravenous APAP treatment (1 g every 6 h) ( Reference Pickering, Schneider and Papet 154 )
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