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Findings of abnormal activation of the HGF/c-MET axis in malignant plasma cells, as well as in the MM microenvironment, also in direct correlation with progressive disease, strongly provide support to the use of drugs targeting this pathway to break the crosstalk between myeloma and accessory cells and, possibly, to restore drug sensitivity
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[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Yokoyama M., Yokoyama A., Yokoyama T., Funazu K., Hamana G., Kondo S., Yamashita T., Nakamura H
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