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RT-PCR assay was used to detect the mRNA expression of CGRP in the injured sciatic nerve tissue
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The presence of fibrosis was negatively associated with SOCS3 gene promoter methylation and positively associated with mRNA expression of SOCS3, TXNIP, IL-6, and MCP-1, which are involved in oxidative stress, inflammation, and fibrogenesis [335]
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