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At *therapeutic* doses, what is the primary metabolic pathway for acetaminophen (paracetamol)? Phase Il conjugation (glucuronidation and sulfation) Phase I oxidation by CYP3A4 Phase I oxidation by CYP2E1 Direct excretion by the
And these components physically interact with a large number of target proteins in the cytoplasm and nucleus (Srinivasan et al., 2007
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