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107 A statistical analysis of three randomized controlled trials with a combined total of 168 participants found curcumin supplementation, at doses of 500–1,500 mg per day, led to improvements in fasting glucose, insulin levels, measures of insulin sensitivity, and HDL- and total cholesterol in women with PCOS

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Gene expression datasets indicated that HIF-1α and HIF-2α were enriched in cells from NDMM patients compared to those from healthy donors (126, 127)