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However, hydroxychloroquine has been shown to confer a survival benefit in patients with SLE, and its omission therefore requires clear justification

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Segmented filamentous bacteria ( SFB ) in the mouse gut promote the production of IL-17 and IFN-γ and play key roles in both osteoclast and osteoblast formation (221–223), indicating that the GM modulates bone metabolism by altering the host immune status

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