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Currently, 255 clinical trials for 5-AZA with chemotherapy and 175 clinical trials for DAC with chemotherapy have already been registered (clinicaltrials.gov)
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These agents act to break apart the mucus bundles from their compacted, tangled state to reduce viscoelasticity and improve clearance, but they are still in the early stages of testing to determine how effective the new mucolytics are compared to the older N-acetylcysteine and carbocysteine
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